Intermittent explosive disorder (abbreviated IED) is a behavioral disorder characterized by extreme expressions of anger, often to the point of violence, that are disproportionate to the situation at hand. It is currently categorized in the Diagnostic and Statistical Manual of Mental Disorders as an impulse control disorder. IED belongs to the larger family of Axis I impulse control disorders listed in the DSM-IV-TR, along with kleptomania, pyromania, pathological gambling, and others.[1] Impulsive aggression is unpremeditated, and is defined by a disproportionate reaction to any provocation, real or perceived.

Treatment is partially achieved through psychotropic medication regimens, though the pharmaceutical options have shown limited success[7]. Multiple drug regimens are frequently indicated for IED patients. Tricyclic antidepressants appear to  alleviate some pathopsychological symptoms; the reasons for such will be explained further in the subsequent section.[2][8] GABAergicmood stabilizers and anticonvulsive drugs such as gabapentin, lithium, carbamazepine, and divalproex seem to aid in controlling the incidence of outbursts.[2][5][9] Anxiolytics help alleviate tension and may help reduce explosive outbursts by increasing the provocative stimulus tolerance threshold, and are especially indicated in patients with comorbid obsessive-compulsive or other anxiety disorders.

Tricyclic Antidepressants
Many side effects may be related to the antimuscarinic properties of the TCAs. Such side effects are relatively common and may include dry mouth, dry nose, blurry vision, lowered gastrointestinal motility or constipation, urinary retention, cognitive and/or memory impairment, and increased body temperature.
Other side effects may include drowsiness, anxiety, emotional blunting (apathy/anhedonia), confusion, restlessness, dizziness,akathisia, hypersensitivity, changes in appetite and weight, sweating, sexual dysfunction, muscle twitches, weakness, nausea and vomiting, hypotension, tachycardia, and rarely, irregular heart rhythms.Twitching, hallucinations, delirium and coma are also some of the toxic effects caused by overdose.

-Wikipedia